ABflo 647 Rabbit anti-Mouse Integrin alpha 2/CD49b mAb

Enables amyloid-beta binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell migration; and positive regulation of cellular component organization. Predicted to act upstream of or within cell adhesion. Located in basal part of cell and external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and genitourinary system. Human ortholog(s) of this gene implicated in several disorders, including Behcet's disorder; artery disorder (multiple); blood platelet disorder (multiple); diabetes mellitus (multiple); and von Willebrand's disorder (multiple). Orthologous to human ITGA2 (integrin subunit alpha 2).