ABflo 488 Rabbit anti-Rat ICAM-1/CD54 mAb

Enables integrin binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipid; and gonad development. Located in cell surface; extracellular space; and plasma membrane. Used to study diabetic angiopathy; mesenteric vascular occlusion; nephritis; pre-eclampsia; and uveitis. Biomarker of several disorders, including cerebrovascular disorder (multiple); colitis (multiple); kidney failure (multiple); lung disorder (multiple); and pancreatitis (multiple). Human ortholog(s) of this gene implicated in several disorders, including autoimmune disorder (multiple); biliary atresia; diabetic retinopathy; inflammatory bowel disorder (multiple); and liver cirrhosis. Orthologous to human ICAM1 (intercellular adhesion molecule 1).