ABflo 647 Rabbit anti-Mouse CXCR2/IL-8RB mAb

Enables chemokine receptor activity. Acts upstream of or within negative regulation of apoptotic process. Predicted to be located in several cellular components, including cell surface; mast cell granule; and mitotic spindle. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; epithelium; and heart. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; acute pyelonephritis; end stage renal disorder; and urinary bladder cancer. Orthologous to human CXCR2 (C-X-C motif chemokine receptor 2).